Attending to tendons

Tendons – time to revisit inflammation

It is currently widely accepted among clinicians that chronic tendinopathy is caused by a degenerative process devoid of inflammation. Current treatment strategies are focused on physical treatments, peritendinous or intratendinous injections of blood or blood products and interruption of painful stimuli. Results have been at best, moderately good and at worst a failure. The evidence for non-in...

Is inflammation harmless to loaded tendons?

Response to mechanical loading in healing tendons

........................................................................................... 7 Populärvetenskaplig sammanfattning ............................................. 9 List of papers .................................................................................. 11 Abbrevations .................................................................................. 13 Introduction ..........

Connecting muscles to tendons: tendons and musculoskeletal development in flies and vertebrates.

The formation of the musculoskeletal system represents an intricate process of tissue assembly involving heterotypic inductive interactions between tendons, muscles and cartilage. An essential component of all musculoskeletal systems is the anchoring of the force-generating muscles to the solid support of the organism: the skeleton in vertebrates and the exoskeleton in invertebrates. Here, we d...

Making tendons

10.1083/jcb/1722fta2jcb1722fta2Mitch [email protected] aking tendons C ells are fastidious about their internal conditions. But for scientists trying to decipher how collagen forms structures such as tendons and the cornea, the big question 30 years ago was how much control cells exert over their surroundings. In a tendon, for example, colla...